Ciprofol is as effective as propofol in patients undergoing gynaecological surgery suggests a recent study published in the BMC Anesthesiology. Ciprofol is a recently developed, short-acting γ-aminobutyric acid receptor agonist sedative that is more potent than propofol. Still, there have been few clinical studies of this agent to date. Here, we sought to examine the safety...

Ciprofol is as effective as propofol in patients undergoing gynaecological surgery suggests a recent study published in the BMC Anesthesiology.

Ciprofol is a recently developed, short-acting γ-aminobutyric acid receptor agonist sedative that is more potent than propofol. Still, there have been few clinical studies of this agent to date. Here, we sought to examine the safety and efficacy of ciprofol use for the induction of general anaesthesia in individuals undergoing gynaecological surgery.

Women between the ages of 18 and 60 years (ASA physical status 1 or 2) who were scheduled to undergo elective gynaecological surgery under general anaesthesia were randomly assigned to two equally sized groups in which anaesthesia induction was performed using either ciprofol or propofol. General anaesthesia induction success rates were the primary outcome for this study, while secondary outcomes included changes in BIS during the 10 min following the first administration of the study drug, the duration of successful induction, and adverse event incidence.

The results of the study are:

Thus, Ciprofol exhibits comparable efficacy to that of propofol when used for the induction of general anaesthesia in individuals undergoing gynaecological surgery and is associated with fewer adverse events.

Chen, Bz., Yin, Xy., Jiang, Lh. et al. The efficacy and safety of ciprofol use for the induction of general anaesthesia in patients undergoing gynaecological surgery: a prospective randomized controlled study. BMC Anesthesiol 22, 245 (2022). https://doi.org/10.1186/s12871-022-01782-7

Ciprofol, effective, propofol, patients, undergoing, gynaecological, surgery, BMC Anesthesiology, Ben-zhen Chen, Xin-yu Yin, Li-hua Jiang, Jin-hui Liu, Yan-yan Shi & Bi-ying Yuan

Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.