Poison Ivy is known for manipulating nature to bring about the end of humanity but this latest plot will literally create The Last of Us.

The following contains spoilers for Poison Ivy #1, on sale now from DC Comics.

Poison Ivy (aka Pamela Isley) is known for using plants to spread her message, even if that message would end humanity as we know it. However, when she became powerful enough to destroy all of Gotham, she gave it all up for love. Even though that was the right choice, she's now regretting her decision. Obsessed with what she had lost, she is now trying to get it all back by creating one of video games' most horrifying apocalypses.

Poison Ivy #1 (by G. Willow Wilson, Marcio Takara, Arif Prianto and Hassan Otsmane-Elhaou) sees Pamela taking a road trip that could end the world. Her plan for achieving her ambitions is the use of a parasitic fungus called Ophiocordyceps. This real-life fungus can burrow into the brains of organisms, taking control of their motor functions before killing them, essentially turning them into "zombies". Though no real-life species can affect humans, Pamela has created her own special strain, the Ophiocordyceps Lamia, and it bears a horrifying resemblance to the fungus from The Last of Us.

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In The Last of Us (2013), the Ophiocordyceps fungus was the cause of the game's zombie apocalypse. Having been adapted to infect humans, it quickly spread and caused the end of civilization. The fungus took control of countless humans, as it does to many other species in nature, and turned them into violent, animalistic zombies with horrifying fungi growing out of their heads.

The first issue of Poison Ivy opens with the titular character spreading her own evolved form of this fungus to various wildlife around her. She began with cattle and swiftly moved on to the farmers who owned them. She eventually killed a few other people that way as well, all in a horrifying fashion. Even though she claimed it was a pleasant and humane death, that didn't stop it from being a spine-chilling display of pure body horror.

Pamela's plan is to reshape the world using this fungus and help nature reclaim everything that humanity has taken from it. She wants to save the world, although she clearly doesn't know all the details of what she has unleashed. This comic and the 2013 video game don't just share a real-world inspiration, they also seem to share the same result. The end of the issue showed that the latest victims of the fungus weren't just a couple of dead corpses. Long after Poison Ivy had killed them, a finger on one of the infected bodies moved.

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The exact nature of Pamela's plot here was originally explored in the Gotham Villains Anniversary Giant #1 story "Ophiocordyceps Lamia" (by G. Willow Wilson, Emma Rios, Jordie Bellaire and Hassan Otsmane-Elhaou). In the story it let its victims experience a state of euphoria as it kills them. It also expanded on what's likely to happen in this series, with those infected becoming linked to The Grey, the opposite of The Green -- the elemental force that connects all plant life in the DC Universe.

It's a terrifying concept based on reality. While the video game explores what the world would look like after such an infection, Poison Ivy will seek to show exactly how this apocalypse will come about. They're two different journeys with the same horrific ending. This series will dive deep into Poison Ivy's character, and the deeper connection the fungus has with nature and DC's elemental forces. Going forward this unique take will set it apart from the game, but the lingering threat will most likely remind some readers of certain details found in The Last of Us.